RSS newsfeed: Genital herpes

Conclusions. Modifiable risk factors for HIV-1 transmission were plasma HIV-1 RNA level and condom use, and, in HIV-1-uninfected partners, herpes simplex virus 2 infection, genital ulcers, Trichomonas vaginalis, vaginitis or cervicitis, and male circumcision. PMID: 22241800 [PubMed - as supplied by publisher] (Source: Herpes)

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Authors: Galeone M, Colucci R, D'Erme AM, Moretti S, Lotti T Abstract Behçet's disease is a multisystem inflammatory disorder characterized by recurrent oral aphthous ulcers, genital ulcers, uveitis, and skin lesions. The cause of Behçet's disease remains unknown, but epidemiologic findings suggest that an autoimmune process is triggered by an environmental agent in a genetically predisposed individual. An infectious agent could operate through molecular mimicry, and subsequently the disease could be perpetuated by an abnormal immune response to an autoantigen in the absence of ongoing infection. Potentia bacterial are Saccharomyces cerevisiae, mycobacteria, Borrelia burgdorferi, Helicobacter pylori, Escherichia coli, Staphylococcus aureus, and Mycoplasma fermentans, but the most...

Conclusions  Sexually transmitted infections have contributed significantly to the spread of HIV in South Africa, but STI control efforts have had limited impact on HIV incidence because of their late introduction and suboptimal coverage.Objectifs:  Evaluer la mesure dans laquelle les infections sexuellement transmissibles (IST) ont contribuéà la propagation du VIH en Afrique du sud et estimer dans quelle mesure des améliorations dans le traitement des IST ont réduit l’incidence du VIH.Méthodes:  Un modèle mathématique a été utilisé pour simuler les interactions entre le VIH et six autres IST (herpès génital, syphilis, chancre mou, blennorragie, infection à Chlamydia et à Trichomonas) ainsi que la vaginose bactérienne et la candidose vaginale. Les effets des IST sur ...

Authors: Shestakov A, Jenssen H, Nordström I, Eriksson K Abstract We have evaluated the potential of bovine lactoferrin and lactoferricin for their ability to prevent and/or treat genital HSV-2 infection in mice. We confirm previous data showing that both lactoferrin and lactoferricin have antiviral properties in vitro and can inhibit HSV-2 infection of GMK cells in a dose-dependent manner. When tested in vivo, lactoferricin but not lactoferrin was also a potent inhibitor of HSV-2 infection. When admixed with virus prior to inoculation, lactoferricin inhibited disease development and significantly reduced the viral load in a genital model of HSV-2 infection in mice. Lactoferrin and lactoferricin were also tested for their ability to stimulate the production of chemokines. Neither ...

A study published in the New England Journal of Medicine reveals that an investigational vaccine protected some women against infection from one of the two types of herpes simplex viruses that cause genital herpes. Leading author Robert Belshe, M.D., director of the Saint Louis University Center for Vaccine Development commented: "There is some very good news in our findings. We were partially successful against half of the equation - protecting women from genital disease caused by HSV-1... (Source: Health News from Medical News Today)

According to a study in which three trials of antiviral therapy to treat genital herpes were combined, the herpes simplex virus type 2/HSV-2 can reactivate in 'breakthrough episodes' even when doses of antiviral therapy are high. The study is published Online First in The Lancet and suggests that new therapies should be conducted to successfully prevent further transmission of this common infection, which affects one in five people... (Source: Health News from Medical News Today)

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The results are disappointing for many, but some see it as a step toward success. WebMD Health News (Source: Medscape Today Headlines)

Vaccine only protected against HSV-1 strain, but not HSV-2 - the most common cause of genital herpes (Source: Health News: CBSNews.com)

People with genital herpes can still infect their sex partners -- even if they are taking anti-herpes drugs that prevent herpes outbreaks. (Source: WebMD Health)

A potential vaccine for genital herpes has shown limited effectiveness in thwarting one type of the sexually transmitted virus. (Source: USATODAY.com Health)

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Results of a clinical trial show that an investigational vaccine for genital herpes protected some women against infection from one of the two strains of virus that cause the disease. Although the results show only partial success, the researchers who conducted the trial believe they represent progress towards a genital herpes vaccine. They write about their findings in the 5 January online issue of the New England Journal of Medicine... (Source: Health News from Medical News Today)

(Source: eMedicineHealth.com)

CONCLUSIONS: In a study population that was representative of the general population of HSV-1- and HSV-2-seronegative women, the investigational vaccine was effective in preventing HSV-1 genital disease and infection but not in preventing HSV-2 disease or infection. (Funded by the National Institute of Allergy and Infectious Diseases and GlaxoSmithKline; ClinicalTrials.gov number, NCT00057330.). PMID: 22216840 [PubMed - in process] (Source: Herpes)

Suppressive medicine for genital herpes reduces the number and duration of outbreaks but does not appear to prevent viral shedding that can result in transmission of virus. Medscape Medical News (Source: Medscape Today Headlines)

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New research points investigators toward finding a genital herpes vaccine that works on both viruses that cause disease. (Source: ScienceDaily Headlines)

It's back to the drawing board for researchers seeking to develop a vaccine that protects against genital herpes. (Source: WebMD Health)

Only partially effective against one type of virus, ineffective against second type, study found Source: HealthDay Related MedlinePlus Pages: Genital Herpes, Immunization, Sexually Transmitted Diseases (Source: MedlinePlus Health News)

A potential vaccine for genital herpes has shown only limited effectiveness in thwarting one type of the sexually transmitted virus and no ability to stop a second type from spreading, a new study shows. (Source: RWJF News Digest - Public Health)

(Saint Louis University) New NIH-funded research points investigators toward finding a genital herpes vaccine that works on both viruses that cause disease. (Source: EurekAlert! - Social and Behavioral Science)

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This study assessed the epidemiology of sexually transmitted infections (STIs), HIV, and associated risk factors among female sex workers (FSWs) in Guangxi autonomous region, China. A cross-sectional study of 488 FSWs was conducted using a structured questionnaire to collect sociodemographic and behavioral information. Biological specimens from subjects were sampled to detect various STIs and HIV infection. Among FSWs, the prevalence rates of syphilis, Neisseria gonorrhoeae, Chlamydia trachomatis, genital herpes, condyloma acuminate, and HIV were 7.2%, 1.8%, 18.2%, 0.4%, 2.3%, and 0.8%, respectively. The prevalence rates of single, double, and triple infections were 22.3%, 3.9%, and 0.20%, respectively. Multivariate analysis indicated that STIs and HIV infection was independently related t...